Thermo Fisher Scientific PTPRE Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human PTPRE (NP_006495.1). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PTPRE,uniProtId:P23469-1,ncbiNodeId:9606,antigenRange:20-200,antigenLength:700,antigenImageFileName:PA5-121078_PTPRE_P23469-1_Rabbit.svg,antigenImageFileNamePDP:PA5-121078_PTPRE_P23469-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.984 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914650

Product Specific Information

Positive test controls include: HL-60, SW620, Mouse brain, Mouse spleen, Mouse lung, Rat brain, Rat lung. The target is usually found in the following locations: Cell membrane, Cytoplasm, Cytoplasm, Single-pass type I membrane protein.

Immunogen sequence: LRGNETTADS NETTTTSGPP DPGASQPLLA WLLLPLLLLL LVLLLAAYFF RFRKQRKAVV STSDKKMPNG ILEEQEQQRV MLLSRSPSGP KKYFPIPVEH LEEEIRIRSA DDCKQFREEF NSLPSGHIQG TFELANKEEN REKNRYPNIL PNDHSRVILS QLDGIPCSDY INASYIDGYK E

Target Information

The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.