Thermo Fisher Scientific PTPRE Polyclonal Antibody
PTPRE 단백질을 표적하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. Western blot, IHC, ELISA 등 다양한 응용에 적합하며, 고순도의 Affinity 정제 및 안정적인 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5121078
- 판매단위
- pk
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1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PTPRE Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 20–200 of human PTPRE (NP_006495.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.984 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914650 |
Product Specific Information
- Positive test controls: HL-60, SW620, Mouse brain, Mouse spleen, Mouse lung, Rat brain, Rat lung
- Subcellular localization: Cell membrane, Cytoplasm, Single-pass type I membrane protein
Immunogen sequence:
LRGNETTADS NETTTTSGPP DPGASQPLLA WLLLPLLLLL LVLLLAAYFF RFRKQRKAVV STSDKKMPNG ILEEQEQQRV MLLSRSPSGP KKYFPIPVEH LEEEIRIRSA DDCKQFREEF NSLPSGHIQG TFELANKEEN REKNRYPNIL PNDHSRVILS QLDGIPCSDY INASYIDGYK E
Target Information
The protein encoded by this gene belongs to the protein tyrosine phosphatase (PTP) family, which regulates various cellular processes such as cell growth, differentiation, mitotic cycle, and oncogenic transformation.
Two alternatively spliced transcript variants have been identified:
- A receptor-type PTP with a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains.
- A nonreceptor-type isoform with a distinct hydrophilic N-terminus.
Studies in mice suggest regulatory roles of this PTP in RAS-related signal transduction, cytokine-induced SATA signaling, and activation of voltage-gated K⁺ channels.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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