Thermo Fisher Scientific Spectrin beta III (SPTBN2) Recombinant Rabbit Monoclonal Antibody (SPTBN2/3142R)
Spectrin beta III (SPTBN2) 단백질을 표적하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. 다양한 응용 분야(WB, IHC, ICC, Flow, ELISA)에 사용 가능. 높은 특이성과 재현성을 제공하며, HEK293 세포에서 발현된 IgG 형 항체로 연구용으로 최적화됨.
- 카탈로그번호
- 6712-RBM9-Px (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Spectrin beta III (SPTBN2) Recombinant Rabbit Monoclonal Antibody (SPTBN2/3142R)
Thermo Fisher Scientific Spectrin beta III (SPTBN2) Recombinant Rabbit Monoclonal Antibody (SPTBN2/3142R)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| ELISA | 2–4 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SPTBN2/3142R |
| Immunogen | Recombinant fragment (around aa356–475) of human SPTBN2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Spectrins are principal components of the cell membrane-cytoskeleton, composed of two alpha and two beta spectrin subunits. The SPTBN2 gene encodes spectrin beta non-erythrocytic 2 (beta-III spectrin), distinct from beta-II spectrin (SPTBN1). SPTBN2 regulates glutamate signaling by stabilizing the glutamate transporter EAAT4 at the plasma membrane surface. Mutations in this gene are associated with spinocerebellar ataxia type 5 (SCA5), characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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