Thermo Fisher Scientific SCD Polyclonal Antibody
Thermo Fisher Scientific의 SCD Polyclonal Antibody는 인간 SCD 단백질을 인식하는 rabbit polyclonal 항체로, Western blot과 면역형광(ICC/IF)에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS와 30% glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide made to an internal portion of the human protein (within residues 50–100). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 30% glycerol |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11152566 |
Product Specific Information
Suggested positive control: whole normal human liver lysate.
Target Information
Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids. The principal product of SCD is oleic acid, which is formed by desaturation of stearic acid.
The ratio of stearic acid to oleic acid has been implicated in the regulation of cell growth and differentiation through effects on cell membrane fluidity and signal transduction.
Four SCD isoforms (Scd1–Scd4) have been identified in mouse, while two (SCD1 and SCD5) are found in humans. SCD1 shares about 85% amino acid identity with all four mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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