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Thermo Fisher Scientific Phospho-53BP1 (Thr543) Polyclonal Antibody
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Thermo Fisher Scientific Phospho-53BP1 (Thr543) Polyclonal Antibody

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Phospho-53BP1 (Thr543) 특이적 폴리클로날 항체로, 인간 및 비인간 영장류 시료에 반응합니다. Western blot에 적합하며, DNA 손상 반응 및 종양 억제 연구에 활용됩니다. 항원 친화 크로마토그래피로 정제된 비결합 액상 항체입니다.

카탈로그번호
PA517000
판매단위
pk
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마지막 업데이트 2025. 08. 05. 오후 07:41
Thermo Fisher Scientific PA517000 Phospho-53BP1 (Thr543) Polyclonal Antibody 100 ul pk판매 단위 pk ·
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629,600원VAT 포함 692,560원

Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-53BP1 (Thr543) Polyclonal Antibody

Applications

Western Blot (WB)

  • Tested Dilution: 1:1,000

Product Specifications

항목 내용
Species Reactivity Human, Non-human primate
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Synthetic phosphopeptide corresponding to residues surrounding pThr543 of human 53BP1
Conjugate Unconjugated
Form Liquid
Purification Antigen affinity chromatography
Storage buffer 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol
Contains No preservative
Storage conditions -20°C
Shipping conditions Ambient (domestic); Wet ice (international)
RRID AB_10983578

Product Specific Information

It is not recommended to aliquot this antibody.


Target Information

53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to the presumptive sites of damage, specifically double-strand breaks. 53BP1 may have a role in checkpoint signaling during mitosis, enhances TP53-mediated transcriptional activation, and participates in DNA repair by maintaining genomic stability.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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