Thermo Fisher Scientific ACL Polyclonal Antibody
ATP citrate lyase 타깃의 Rabbit Polyclonal Antibody로 Western blot 및 Immunoprecipitation에 적합. Human, Mouse 반응성 보유. 항원 친화 크로마토그래피로 정제된 액상 형태, 4°C 보관. 연구용으로만 사용.
- 카탈로그번호
- A303866A
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 350 and 400 of human ATP citrate lyase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Rat, Sheep, and Bovine
Target Information
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues.
The enzyme is a tetramer (molecular weight ≈ 440,000) of identical subunits.
It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with hydrolysis of ATP to ADP and phosphate.
Acetyl-CoA serves several biosynthetic pathways, including lipogenesis and cholesterogenesis.
In nervous tissue, ATP citrate lyase may be involved in acetylcholine biosynthesis.
Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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