Thermo Fisher Scientific SAMD8 Polyclonal Antibody
SAMD8 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 Human에 반응. 합성 펩타이드 면역원 사용, 액상 형태로 제공. 장기 보관 시 -20°C에서 소분 보관 권장.
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Thermo Fisher Scientific SAMD8 Polyclonal Antibody
Applications
- Western Blot (WB): 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human SAMD8 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2884653 |
Product Specific Information
- Immunogen sequence: MQTYPPLPDI FLDSVPRIPW AFAMTEVCGM ILCYIWLLVL LLHKHRSILL
- Storage guidance:
- Short term: 2–8°C up to 1 week
- Long term: -20°C in small aliquots to prevent freeze-thaw cycles
- Predicted homology: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish — all 100%
Target Information
Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group onto the primary hydroxyl of ceramide.
SAMD8 is an endoplasmic reticulum (ER) transferase that lacks sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) with low product yield.
It operates as a ceramide sensor controlling ceramide homeostasis in the ER rather than converting ceramides. SAMD8 is critical for maintaining the integrity of the early secretory pathway. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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