Thermo Fisher Scientific Phospho-RET (Tyr1062) Polyclonal Antibody
RET 단백질의 Tyr1062 인산화 부위를 인식하는 폴리클로날 항체로, Western blot에 최적화되어 있습니다. 인간에 반응하며, 마우스·랫·개에서도 예측 반응성을 보입니다. 항원 친화 크로마토그래피로 정제되었으며, 연구용으로만 사용됩니다.
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Thermo Fisher Scientific Phospho-RET (Tyr1062) Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of Human Ret (phospho Tyr1062). The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.37 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736417 |
Product Specific Information
- Positive Control: K562
- Predicted Reactivity: Mouse (100%), Rat (100%), Dog (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development and can undergo oncogenic activation by cytogenetic rearrangement. RET transduces signals for cell growth and differentiation.
Mutations in the RET gene are associated with multiple endocrine neoplasia types IIA and IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for the RET gene. Additional transcript variants have been described but their biological validity has not been confirmed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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