Thermo Fisher Scientific SPIN90 Polyclonal Antibody
Thermo Fisher Scientific의 SPIN90 Polyclonal Antibody는 Rabbit IgG 기반 항체로 다양한 응용 분야(WB, IHC, IP)에 사용 가능. Human SH3 단백질(NCKIPSD, Q9NZQ3-1) 특정 부위(672–722)를 면역원으로 제작. 액상 형태로 4°C 보관, 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:200–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 672 and 722 of Human SH3 protein interacting with Nck, 90 kDa (NCKIPSD, UniProt ID: Q9NZQ3-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
The protein encoded by this gene is localized exclusively in the cell nucleus. It plays a role in signal transduction and may function in the maintenance of sarcomeres and the assembly of myofibrils into sarcomeres. It also contributes to stress fiber formation.
This gene is involved in therapy-related leukemia by chromosomal translocation t(3;11)(p21;q23) involving the myeloid/lymphoid leukemia gene. Alternative splicing yields two transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: A302-647A-M_NCKIPSD_Q9NZQ3-1_Rabbit.svg, A302-647A-M_NCKIPSD_Q9NZQ3-1_Rabbit_PDP.jpeg)
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