Thermo Fisher Scientific GABARAP Polyclonal Antibody
GABARAP 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC에 사용 가능. Human, Mouse, Rat 반응성. Lyophilized 형태로 제공되며, 4°C 단기 보관 및 -20°C 장기 보관 권장. GABAA 수용체 관련 단백질 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:100–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the N-terminal region of human GABA(A) receptor-associated protein (GABARAP) conjugated to an immunogenic carrier protein. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 150 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: GABARAP (L1, L2).
Target Information
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the central nervous system, increasing Cl⁻ conductance to inhibit neuronal firing.
It acts through ionotropic (GABAA) and metabotropic (GABAB) receptors, as well as GABAC receptors.
GABARAP (GABAA receptor-associated protein) links GABAA receptors to the cytoskeleton and may play a role in intracellular transport and receptor-cytoskeleton interactions.
GABARAP belongs to the MAP1 or ATG8-like family. Recent studies show that MAPK15/ERK8 interacts with ATG8 family proteins to regulate autophagy.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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