Thermo Fisher Scientific Prohibitin Polyclonal Antibody

Applications

Immunohistochemistry (IHC)

• Tested Dilution: 1:100–1:500

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:100–1:500

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, predicted to react with Mouse, Rat, Bovine, Dog, Rabbit, Guinea pig, Pig, Panda, Cat, Orangutan, Monkey, Gorilla, Chimpanzee, and Chinese hamster

Target Information

Prohibitin is an evolutionarily conserved gene expressed ubiquitously. It functions as a negative regulator of cell proliferation and may act as a tumor suppressor. Mutations in the PHB gene have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of the 3′ untranslated region, with the longer transcript present at higher levels in proliferating tissues and cells, suggesting a regulatory role as a trans-acting RNA.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.