Thermo Fisher Scientific PSMF1 Monoclonal Antibody (OTI2D7), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:200–1:2,000

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100

Product Specifications

Target Information

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of two complexes: a 20S core and a 19S regulator.

• The 20S core is composed of four rings of 28 non-identical subunits (two rings of seven alpha subunits and two rings of seven beta subunits).
• The 19S regulator consists of a base (six ATPase subunits and two non-ATPase subunits) and a lid (up to ten non-ATPase subunits).
  Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal process.
  The immunoproteasome plays a key role in processing class I MHC peptides.
  This gene encodes a protein that inhibits proteasome activation by the 11S and 19S regulators. Alternative transcript variants have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.