Thermo Fisher Scientific CHRM2 Recombinant Rabbit Monoclonal Antibody (23GB5875)
CHRM2 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 유세포 분석에 적합합니다. HEK293F 발현 시스템에서 생산되었으며, 고순도 친화 크로마토그래피 정제 제품입니다. 인간, 생쥐, 랫트 반응성이 확인되었습니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Flow Cytometry (Flow)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB5875 |
| Immunogen | A synthesized peptide derived from human ACM2 (152–180AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Muscarinic cholinergic receptor 2 (CHRM2) is an acetylcholine receptor suggested to function as a presynaptic autoreceptor that inhibits acetylcholine release. The M2 receptor may also mediate smooth muscle contractility. In Alzheimer’s disease, selective loss of M2 subtype receptors occurs in cortical and hippocampal regions of the human brain. Increased M2 receptor heterozygosity has been associated with depression in women. M2 receptor expression has been reported in the cerebellum, cerebral cortex, hippocampus, medulla, striatum, thalamus, lung, and prostate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: MA5-52936_CHRM2_P08172-1_Rabbit.svg, MA5-52936_CHRM2_P08172-1_Rabbit_PDP.jpeg)
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