Thermo Fisher Scientific SNCB Polyclonal Antibody, MaxPab
SNCB 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 시료에서 반응하며 Western Blot에 적합합니다. 액상 형태로 제공되며 PBS 버퍼에 보존, -20°C 보관이 필요합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
- Publications: 없음
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | SNCB (NP_001001502.1, 1–134 a.a), full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MDVFMKGLSM AKEGVVAAAE KTKQGVTEAA EKTKEGVLYV GSKTREGVVQ GVASVAEKTK EQASHLGGAV FSGAGNIAAA TGLVKREEFP TDLKPEEVAQ EAAEEPLIEP LMEPEGESYE DPPQEEYQEY EPEA
Target Information
Synuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals. In vertebrates, they are encoded by three different genes. Synucleins have been implicated in major diseases such as Alzheimer’s (AD), Parkinson’s (PD), and breast cancer.
- In AD, a peptide derived from alpha synuclein forms a component of plaque amyloid.
- In PD, alpha synuclein accumulates in Lewy bodies, and its allele is linked to familial PD cases.
- In breast cancer, increased expression of gamma synuclein correlates with disease progression.
Synucleins appear to play a role in membrane plasticity in the developing song control system of songbirds.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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