Thermo Fisher Scientific Progesterone Monoclonal Antibody (6-5E-3F)
프로게스테론을 특이적으로 인식하는 마우스 단클론 항체로, RIA 및 Peptide Array 등 다양한 분석에 사용 가능. ELISA 검증 완료. 고순도 Protein A/G 정제, 보존제 무첨가 PBS 용액 형태. 연구용으로만 사용.
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Thermo Fisher Scientific Progesterone Monoclonal Antibody (6-5E-3F)
Applications
- Radioimmune Assays (RIA): Assay-dependent
- Peptide Array (Array): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chemical |
| Host/Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6-5E-3F |
| Immunogen | Progesterone hemisuccinate conjugated to bovine serum albumin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C or -80°C if preferred |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Antibody is tested in direct ELISA.
Target Information
Progesterone is the major progestational steroid, secreted primarily by the corpus luteum and the placenta.
It binds to the progesterone receptor, leading to dissociation of heat shock proteins, receptor phosphorylation, and transcription activation through direct or indirect interaction with transcription factors.
Progesterone acts on the uterus, mammary glands, and brain, and is essential for embryo implantation, pregnancy maintenance, and mammary tissue development for milk production.
Converted from pregnenolone, it also serves as an intermediate in the biosynthesis of gonadal steroid hormones and adrenal corticosteroids.
Therapeutic progesterone is a synthetic form of the endogenous hormone that inhibits estrogen effects by decreasing estrogen receptor numbers and increasing metabolism to inactive metabolites.
(Source: National Center for Biotechnology Information. PubChem Compound Database; CID=5994)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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