Thermo Fisher Scientific KCTD13 Polyclonal Antibody
KCTD13 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. WB 및 IHC에 사용 가능하며, 인간 시료에 반응. 합성 펩타이드 면역원으로 제작되어 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.2–1 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | 5 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human KCTD13 (aa 26–75) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2606316 |
Product Specific Information
Peptide sequence:
PGPAAYGLKP LTPNSKYVKL NVGGSLHYTT LRTLTGQDTM LKAMFSGRVE
Sequence homology:
Cow: 93%
Dog: 100%
Human: 100%
Mouse: 93%
Rabbit: 100%
Rat: 93%
Target Information
Cytochrome P450 superfamily proteins are monooxygenases that catalyze various biochemical reactions involved in drug metabolism and the synthesis of cholesterol, steroids, and lipids.
CYP4F3, a 60 kDa protein, is a novel member of this family. It contains a conserved heme-binding domain near the C-terminus and catalyzes the ω-hydroxylation of LTB4.
CYP4F3 is localized in the endoplasmic reticulum and plays an essential role in LTB4 inactivation and inflammation control.
CYP4F3 exists in two distinct isoforms:
- CYP4F3A: Neutrophil isoform, expressed in neutrophils and myeloid cells, catalyzes microsomal ω-hydroxylation of LTB4.
- CYP4F3B: Liver isoform, catalyzes conversion of arachidonic acid to 20-HETE, a potent PKC activator involved in cell proliferation, vascular tone regulation, and natriuresis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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