Thermo Fisher Scientific IFN alpha Monoclonal Antibody (K9)

Applications

Tested Dilution

Publications

Neutralization (Neu)

Assay-dependent

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Miscellaneous PubMed (Misc)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Pig

Published species

Not Applicable

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

K9

Immunogen

Porcine Interferon Alpha

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.66 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 8.0

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_223545

Product Specific Information

Specificity/Activity: Neutralizes pig IFN alpha on A549/MDBK cells in a cytopathic effect inhibition assay.

Purity is >95%. Endotoxin level <1 EU/ug.

Packaged by and distributed for PBL Assay Science.

Target Information

IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha with its receptor component result in the activation of a number of signaling pathways which are mainly involved in innate immune response against viral infection. In humans, the gene for IFN alpha is located on on chromosome 9. The type I interferons consist of 14 different alpha isoforms (subtypes with slightly different specificities), and single beta, omega, epsilon and kappa isoforms. Homologous molecules are found in many species, including rats and mice (and most mammals), and have been identified in birds, reptiles and fish species. IFN alpha is produced primarily by plasmacytoid dendritic cells, is a potent component of the anti-viral innate immune response and modulates adaptive immunity. Diseases associated with the dysfunction of IFN alpha include Hepatitis C and Hepatitis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.