Thermo Fisher Scientific CD49c (Integrin alpha 3) Polyclonal Antibody
Thermo Fisher Scientific의 CD49c (Integrin alpha 3) 폴리클로날 항체는 인간 및 랫트 반응성을 가지며 WB와 IHC(P)에 사용 가능합니다. 고순도 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공합니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human Integrin alpha 3 (51–67aa LFGYSVALHRQTERQQR) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide, 0.05 mg thimerosal |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746644 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
ITGA3 (Integrin alpha-3), also known as CD49C, VLA3, or GAPB3, is encoded by the ITGA3 gene in humans. It is an integrin alpha subunit and a member of the cell surface adhesion molecule family.
- Chromosomal location: 17q21.33
- Forms half of the alpha3beta1 integrin duplex involved in neural migration and corticogenesis
- Linked to DAB1 phosphorylation and ITGA3 signaling for neuronal detachment
- Expression increases viral infectivity in CHO cells
- Contains 13 potential N-glycosylation sites, 2 cleavage sites, and 7 N-terminal repeating units typical of ITGAs
- Recombinant ITGA3 expressed as a 150-kD protein, identical in size to the native protein by Western blot analysis
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA5-79528_CD49c_Integrin_alpha_3_P26006-2_Rabbit.svg, PA5-79528_CD49c_Integrin_alpha_3_P26006-2_Rabbit_PDP.jpeg)
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