Thermo Fisher Scientific BAG5 Polyclonal Antibody
BAG5 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot에 적합하며 인간에 반응, 마우스와 랫트에도 예측 반응. 합성 펩타이드 면역원 사용, 액상 형태로 안정적 보관 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (DPQGEEKCKAARKQ) corresponding to internal amino acids of BAG5 (aa 413–427) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11006100 |
Product Specific Information
- Predicted to react with mouse and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
It has been hypothesized that the BAG-5 protein induces death of nigral neurons through its interaction with hsp70, causing increased protein aggregation and cell death by disinhibition of hsp70’s anti-apoptotic function.
BAG-5 is believed to play an important role in neuronal death mechanisms and may act as a modulator of the hsp70/hsp40 chaperone axis.
It may also coordinate localization and modulation of other BAG-containing proteins via BAG-BAG heterodimerization.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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