Thermo Fisher Scientific CD9 Monoclonal Antibody (EM-04), APC

Thermo Fisher Scientific CD9 Monoclonal Antibody (EM-04), APC

Applications

• Flow Cytometry (Flow)

Tested Dilution: 2–3 µg/mL
Publications: -

Product Specifications

Additional Formats

• Unconjugated: MA1-10309
• FITC: MA1-10311
• PE: MA1-10312
• Custom conjugation available on request

Target Information

CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophils, stimulated T lymphocytes, and by neurons and glial cells in the peripheral nervous system.
It belongs to the tetraspanin family, which spans the membrane four times. In pre-B cells and platelets, CD9 regulates cell activation and aggregation, possibly through association with integrin CD41/CD61 (GPIIb/GPIIIa).
CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, sperm-egg fusion, and plays roles in cell attachment and proliferation. It is necessary for heterologous MHC II molecule association on dendritic cells, crucial for effective T cell stimulation.
CD9 functions in differentiation, adhesion, and signal transduction, and its expression is linked to suppression of cancer cell motility and metastasis. It is considered a metastasis suppressor in solid tumors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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