Thermo Fisher Scientific CD9 Monoclonal Antibody (EM-04), APC
APC 형광 표지된 CD9 단클론 항체로 Flow Cytometry에 최적화됨. Rat IgG1 유래 EM-04 클론이며, 세포 표면 CD9 단백질 검출에 사용. 651/660 nm 파장에서 발광하며, 4°C 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific CD9 Monoclonal Antibody (EM-04), APC
Applications
- Flow Cytometry (Flow)
Tested Dilution: 2–3 µg/mL
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rat / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | EM-04 |
| Immunogen | Permeabilized murine bone marrow-derived mast cells (BMMC) |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2534496 |
Additional Formats
- Unconjugated: MA1-10309
- FITC: MA1-10311
- PE: MA1-10312
- Custom conjugation available on request
Target Information
CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophils, stimulated T lymphocytes, and by neurons and glial cells in the peripheral nervous system.
It belongs to the tetraspanin family, which spans the membrane four times. In pre-B cells and platelets, CD9 regulates cell activation and aggregation, possibly through association with integrin CD41/CD61 (GPIIb/GPIIIa).
CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, sperm-egg fusion, and plays roles in cell attachment and proliferation. It is necessary for heterologous MHC II molecule association on dendritic cells, crucial for effective T cell stimulation.
CD9 functions in differentiation, adhesion, and signal transduction, and its expression is linked to suppression of cancer cell motility and metastasis. It is considered a metastasis suppressor in solid tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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