Thermo Fisher Scientific Cyclin F Polyclonal Antibody
Cyclin F 단백질을 인식하는 Rabbit Polyclonal 항체로, 인체 시료에 반응. IHC(P)에서 1:50–1:200 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 세포주기 조절 연구용으로 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: 없음
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Cyclin F. Recombinant protein control fragment (Product # RP-107826) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2662846 |
Product Specific Information
Immunogen sequence:
GDQESEGEKEG DVTAPSGILD VTVVYLNPEQ HCCQESSDEE ACPEDKGPQD PQALALDTQI PATPGPKPLV R
Highest antigen sequence identity to the following orthologs:
- Mouse: 69%
- Rat: 69%
Target Information
This gene encodes a member of the cyclin family. Cyclins regulate cell cycle transitions by binding and activating cyclin-dependent protein kinases.
Cyclin F also belongs to the F-box protein family, characterized by a ~40 amino acid F-box motif.
F-box proteins are subunits of the SCF (SKP1–cullin–F-box) ubiquitin ligase complex, functioning in phosphorylation-dependent ubiquitination.
They are classified into:
- Fbws: Containing WD-40 domains
- Fbls: Containing leucine-rich repeats
- Fbxs: Containing other interaction modules or no recognizable motifs
Cyclin F belongs to the Fbxs class and was one of the first proteins identified with an F-box motif.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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