Thermo Fisher Scientific MCM2 Recombinant Rabbit Monoclonal Antibody (0Q10S9)
MCM2 단백질을 인식하는 재조합 토끼 단일클론 항체로, WB, IHC, ICC/IF, ELISA에 사용 가능. 인간, 생쥐, 랫트 반응성. 핵 내 MCM2 검출에 적합하며, 고순도 친화 크로마토그래피 정제. 연구용으로 DNA 복제 관련 단백질 분석에 활용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 0Q10S9 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1–100 of human MCM2 (P49736) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.38 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911907 |
Product Specific Information
- Positive test controls: HeLa, 293T, C2C12
- Target localization: Nucleus
Immunogen sequence:
MAESSESFTM ASSPAQRRRG NDPLTSSPGR SSRRTDALTS SPGRDLPPFE DESEGLLGTE GPLEEEEDGE ELIGDGMERD YRAIPELDAY EAEGLALDDE
Target Information
MCM2 (Mini chromosome maintenance protein 2) is involved in regulating DNA replication.
MCM2 (also called CDCL1, mitotin, and BM28) is a human nuclear protein crucial for the cell cycle, particularly in the onset of DNA replication and cell division. It is similar to early S-phase proteins and mapped to 3q21. CDCL1 is considered a candidate oncogene affected by chromosomal breaks in acute myeloid leukemia (AML).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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