Thermo Fisher Scientific NFATc1 Polyclonal Antibody
NFATc1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 면역침강(IP)에 최적화됨. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 4°C 보관. 면역 반응 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 175 and 225 of human Nuclear Factor of Activated T-cells, Cytoplasmic, Calcineurin-Dependent 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Pig
Target Information
The product of this gene is a component of the nuclear factor of activated T cells (NFAT) DNA-binding transcription complex.
This complex consists of at least two components:
- A preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation
- An inducible nuclear component
Proteins in this family play a central role in inducible gene transcription during immune response.
The NFATC1 gene product functions as a major molecular target for immunosuppressive drugs such as cyclosporin A.
Five transcript variants encoding distinct isoforms have been identified, which may regulate inducible expression of different cytokine genes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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