Thermo Fisher Scientific ALS2CR8 Polyclonal Antibody
ALS2CR8 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat에 반응합니다. Western blot, IHC, ICC, ELISA 등 다양한 응용에 사용 가능하며, Protein A로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human ALS2CR8 (amino acids 251–350) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CARF (Calcium-Response Factor), also known as ALS2CR8 or NYD-SP24, is a 725 amino acid nuclear protein expressed in various tissues, with the highest levels in the hippocampus. CARF is believed to function as a transcription factor associated with the p53 tumor suppression pathway. It cooperates and co-localizes with ARF (ADP-ribosylation factor) to mediate ARF–p53-induced apoptotic signaling, which is involved in cell cycle control, cellular development, DNA damage response, and aging processes.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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