Thermo Fisher Scientific ARP2/ARP3 Polyclonal Antibody
ARP2/ARP3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 다양한 종(Human, Mouse, Rat, Xenopus)에 반응하며 WB, IHC, ICC, ELISA 등 다중 응용 가능. 고순도 Protein A 정제, 안정적 액상 형태로 연구용에 적합.
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Thermo Fisher Scientific ARP2/ARP3 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat, Xenopus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human ARP2/ARP3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Actin polymerization is essential for various cellular processes such as chemotaxis, migration, adhesion, and platelet activation. The Arp2/3 complex facilitates actin nucleation and branching by interacting with actin filaments, promoting growth in the barbed direction. It also mediates actin cytoskeletal outgrowths regulated by Rho family GTPases. In response to GTP-binding Cdc42, the Arp2/3 complex binds WASP proteins to initiate lamellipodia and filopodia formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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