Thermo Fisher Scientific CD304 (Neuropilin-1) Monoclonal Antibody (5H11G6)
Human CD304 (Neuropilin-1) 단백질을 인식하는 Mouse monoclonal antibody. Western blot 및 ELISA에 최적화. Protein G 정제, 1 mg/mL 농도, PBS buffer에 0.05% sodium azide 함유. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5H11G6 |
| Immunogen | Purified recombinant fragment of human NRP1 (AA: 22–644) expressed in HEK293 cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3091032 |
Target Information
Neuropilin 1 (CD304) is a 923-amino acid membrane-bound coreceptor belonging to the neuropilin family. It contains two CUB domains, two F5/8 type C domains, and a MAM domain. Neuropilin 1 forms heterodimers with Neuropilin 2 (NRP2) and binds to plexin (PLXNB1) to form semaphorin receptors. It is primarily expressed in the nervous system and plays roles in cardiovascular development, angiogenesis, axon guidance, neuronal circuit formation, cell survival, neuronal migration, and organogenesis. Neuropilin 1 also functions as a receptor for semaphorins and VEGF, regulating VEGF-induced angiogenesis. It has been implicated in aggressive prostate carcinoma and breast cancer progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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