Thermo Fisher Scientific GSDMB (Cleaved) Recombinant Rabbit Monoclonal Antibody (6F4K3)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

6F4K3

Immunogen

A synthetic peptide corresponding to residues surrounding Ser245 of human Gasdermin B. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GSDMB (Cleaved),uniProtId:Q8TAX9-4,ncbiNodeId:9606,antigenRange:243-247,antigenLength:416,antigenImageFileName:MA5-55412_GSDMB_Cleaved_Q8TAX9-4_Rabbit.svg,antigenImageFileNamePDP:MA5-55412_GSDMB_Cleaved_Q8TAX9-4_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.11 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Product Specific Information

Immunogen Sequence: GKSLG

Target Information

GSDMB (Cleaved) refers to the gene target Gasdermin B, which undergoes cleavage to produce active fragments. Gasdermin B is a protein that plays a role in the regulation of cell death and inflammation. Cleavage of GSDMB leads to the release of its N-terminal fragment, which can initiate a process called pyroptosis, a type of programmed cell death. Pyroptosis is an inflammatory form of cell death that is triggered by various stimuli, including infection and cellular stress.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.