Thermo Fisher Scientific HK2 Monoclonal Antibody (1798CT748.15.25)
HK2 단백질을 인식하는 mouse monoclonal antibody로 Western blot 및 IHC(P)에서 사용 가능. Human 시료에 반응하며, Protein G로 정제된 액상 형태. 4°C 단기 보관, -20°C 장기 보관 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1798CT748.15.25 |
| Immunogen | Recombinant protein between 1–170 amino acids from human HK2 (Hexokinase II) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Protein G |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897663 |
Target Information
In vertebrates, there are four major glucose-phosphorylating isoenzymes designated hexokinase I, II, III, and IV. Hexokinase activity is involved in the first step of several metabolic pathways, including phosphorylation of glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P. Hexokinase 2 is the predominant isozyme expressed in insulin-responsive tissues such as skeletal muscle. Expression of this gene is insulin-responsive, and studies in rats suggest it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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