Thermo Fisher Scientific Cathepsin H/K/L/V Recombinant Rabbit Monoclonal Antibody (ARC1276)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC1276

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Cathepsin L/V/K/H (P07711) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Cathepsin H/K/L/V,uniProtId:P07711-1,ncbiNodeId:9606,antigenRange:50-150,antigenLength:333,antigenImageFileName:MA5-35614_Cathepsin_HKLV_P07711-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35614_Cathepsin_HKLV_P07711-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:Cathepsin H/K/L/V,uniProtId:O60911-1,ncbiNodeId:9606,antigenRange:50-150,antigenLength:334,antigenImageFileName:MA5-35614_Cathepsin_HKLV_O60911-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35614_Cathepsin_HKLV_O60911-1_Rabbit_PDP.jpeg,sortOrder:2},{targetFamily:Cathepsin H/K/L/V,uniProtId:P09668-1,ncbiNodeId:9606,antigenRange:50-150,antigenLength:335,antigenImageFileName:MA5-35614_Cathepsin_HKLV_P09668-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35614_Cathepsin_HKLV_P09668-1_Rabbit_PDP.jpeg,sortOrder:3},{targetFamily:Cathepsin H/K/L/V,uniProtId:P43235-1,ncbiNodeId:9606,antigenRange:50-150,antigenLength:329,antigenImageFileName:MA5-35614_Cathepsin_HKLV_P43235-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35614_Cathepsin_HKLV_P43235-1_Rabbit_PDP.jpeg,sortOrder:4}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2849514

Product Specific Information

Immunogen sequence: AVWEKNMKMI ELHNQEYREG KHSFTMAMNA FGDMTSEEFR QVMNGFQNRK PRKGKVFQEP LFYEAPRSVD WREKGYVTPV KNQGQCGSCW AFSATGALEG Q

Target Information

The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.