Thermo Fisher Scientific FNIP2 Polyclonal Antibody
FNIP2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 IHC에 사용 가능하며, 인간·마우스·랫트 반응성. 고순도 항원 친화 크로마토그래피 정제, 액상 형태로 1 mg/mL 농도. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide near the carboxy terminus of human FNIP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11157473 |
Product Specific Information
- Suggested positive control: rat skeletal muscle tissue lysate
- PA5-20690 can be used with blocking peptide PEP-0805
Target Information
FNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene. Folliculin functions as a tumor suppressor, and its mutations or loss of heterozygosity are associated with BHD syndrome-related renal tumors. Folliculin and FNIP1, which shares 49% identity with FNIP2, bind to AMPK, an essential energy sensor that negatively regulates mTOR—a key regulator of cell growth and proliferation. FNIP1 and FNIP2 can form homo- and heteromeric multimers, suggesting a functional relationship between them.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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