Thermo Fisher Scientific FNIP2 Polyclonal Antibody
Thermo Fisher Scientific의 FNIP2 Polyclonal Antibody는 인간, 마우스, 랫트 반응성을 가지며 Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제된 비결합 액상 항체로, 2-8°C에서 단기 보관 가능합니다. FNIP2 단백질 연구용으로 최적화된 고품질 항체입니다.
- 카탈로그번호
- PA520691
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB)
Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | An 18 amino acid peptide near the amino terminus of human FNIP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11153176 |
Product Specific Information
- A suggested positive control is mouse skeletal muscle tissue lysate.
- PA5-20691 can be used with blocking peptide PEP-0806.
Target Information
FNIP2 is the second protein found to interact with folliculin, the product of the Birt-Hogg-Dube (BHD) gene. Folliculin acts as a tumor suppressor, as mutations or loss of heterozygosity in this gene are associated with BHD syndrome-related renal tumors.
Folliculin and FNIP1, which shares 49% identity with FNIP2, bind to AMPK—an important energy sensor that negatively regulates mTOR, a key regulator of cell growth and proliferation. FNIP1 and FNIP2 can form homo- and heteromeric multimers, suggesting a functional relationship between these proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-20691_FNIP2_Q9P278-1_Rabbit.svg
- PA5-20691_FNIP2_Q9P278-1_Rabbit_PDP.jpeg
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