Thermo Fisher Scientific HMOX1 Monoclonal Antibody (GT1334)
HMOX1 단백질을 검출하기 위한 Thermo Fisher Scientific의 단클론 항체로, Western blot에 적합합니다. 인간에 반응하며 Mouse, Rat 등에서도 예측 반응성을 가집니다. 단백질 A로 정제된 액상 항체로, 장기 보관 시 -20°C에서 보관합니다.
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Thermo Fisher Scientific HMOX1 Monoclonal Antibody (GT1334)
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT1334 |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Heme Oxygenase 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.09 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787185 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (81%), Rat (80%), Dog (85%), Pig (82%), Bovine (83%).
- Positive Control: HeLa (500 µM CoCl₂ treatment for 24 hr).
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Heme oxygenase (HO) is a microsomal enzyme that catalyzes the oxidation of heme to antioxidant molecules, biliverdin and carbon monoxide.
HO consists of two homologous isozymes: inducible HO-1 and constitutively expressed HO-2.
HO-1 is induced by a wide variety of stimuli including oxidative stress, inflammatory agents, transforming growth factor beta, and heat shock.
Increased expression of HO-1 is considered a cellular defense mechanism against oxidative stress, as elevated HO may generate more bilirubin, an antioxidant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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