Thermo Fisher Scientific CD205 Monoclonal Antibody (NLDC-145)

Applications

Immunohistochemistry (Frozen) (IHC (F))

• Tested Dilution: 1:10 – 1:25

Immunocytochemistry (ICC/IF)

• Tested Dilution: Assay-dependent

Flow Cytometry (Flow)

• Tested Dilution: Assay-dependent
• Publications: 1 publication available

Miscellaneous PubMed (Misc)

• Publications: 1 publication available

Product Specifications

Product Specific Information

Rat anti-Mouse CD205, clone NLDC-145 recognizes DEC-205, an approximately 205 kDa integral membrane glycoprotein expressed by mouse dendritic cells and thymic epithelial cells.

Target Information

CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking, and presentation, enhancing antigen-specific T cell immunity.
CD205 is highly expressed by CD8+ dendritic cells and also found in bone marrow Gr1+ cells, Langerhans cells, bone marrow-derived DCs (BMDC), and thymic epithelial cells.
It functions as an endocytic receptor directing captured antigens to specialized antigen processing regions and can reduce B lymphocyte proliferation.
Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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