Thermo Fisher Scientific CD205 Monoclonal Antibody (NLDC-145)
CD205 (NLDC-145) 단클론 항체로 mouse dendritic cell 및 thymic epithelial cell의 DEC-205 단백질 검출용. IHC, ICC/IF, Flow Cytometry에 사용 가능. 비결합형 액상 형태로 연구용으로 적합.
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Applications
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: 1:10 – 1:25
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
- Publications: 1 publication available
Miscellaneous PubMed (Misc)
- Publications: 1 publication available
Product Specifications
| 항목 | 내용 |
|---|---|
| Published species | Mouse |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | NLDC-145 |
| Immunogen | Mouse lymph node stroma emulsified in Freund’s complete adjuvant |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage conditions | 4°C or -20°C if preferred |
| Shipping conditions | Wet ice |
| RRID | AB_2538367 |
Product Specific Information
Rat anti-Mouse CD205, clone NLDC-145 recognizes DEC-205, an approximately 205 kDa integral membrane glycoprotein expressed by mouse dendritic cells and thymic epithelial cells.
Target Information
CD205 (LY25, Lymphocyte Antigen 75) is an integral membrane glycoprotein involved in antigen uptake, trafficking, and presentation, enhancing antigen-specific T cell immunity.
CD205 is highly expressed by CD8+ dendritic cells and also found in bone marrow Gr1+ cells, Langerhans cells, bone marrow-derived DCs (BMDC), and thymic epithelial cells.
It functions as an endocytic receptor directing captured antigens to specialized antigen processing regions and can reduce B lymphocyte proliferation.
Diseases associated with CD205 dysfunction include pneumonic plague and lipid pneumonia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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