Thermo Fisher Scientific NME1 Monoclonal Antibody (OTI22F6), TrueMAB
NME1 단백질을 인식하는 Mouse Monoclonal Antibody로 Western Blot에 최적화됨. Human 시료 반응성. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI22F6 |
| Immunogen | Full-length human recombinant NME1 protein produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
NME1 was identified due to reduced mRNA transcript levels in highly metastatic cells.
Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of A (encoded by NME1) and B (encoded by NME2) isoforms.
Mutations in NME1 have been associated with aggressive neuroblastomas. Two transcript variants encoding different isoforms have been identified.
Co-transcription of NME1 and the neighboring gene NME2 produces naturally occurring NME1-NME2 fusion transcripts, encoding a protein containing sequences from both genes.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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