Thermo Fisher Scientific CKMT2 Polyclonal Antibody
Rabbit polyclonal antibody targeting CKMT2 for detection of endogenous mitochondrial creatine kinase. Suitable for WB and ICC/IF. Affinity purified, liquid form, 1 mg/mL concentration. For research use only.
- 카탈로그번호
- PA5118822
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CKMT2 (Accession P17540), corresponding to amino acid residues A242–K292 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20 °C |
| Shipping Conditions | Wet ice |
| RRID | AB_2903322 |
Product Specific Information
Antibody detects endogenous levels of total CKMT2.
Target Information
Mitochondrial creatine kinase (MtCK) mediates the transfer of high-energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family and exists as two isoenzymes—sarcomeric MtCK and ubiquitous MtCK—encoded by separate genes. MtCK occurs in dimeric and octameric forms, unlike the exclusively dimeric cytosolic isoenzymes. Sarcomeric MtCK shares ~80% homology with ubiquitous MtCK. The gene contains motifs common to nuclear genes encoding mitochondrial proteins, potentially important for coordinated activation during mitochondrial biogenesis. Three transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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