Thermo Fisher Scientific GPRC6A Polyclonal Antibody
인간 GPRC6A 단백질을 검출하는 Rabbit Polyclonal Antibody로, IHC(P) 등 다양한 응용에 적합합니다. 비결합형 액상 형태이며 1 mg/mL 농도로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA132735
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 17 amino acid peptide from N-terminal extracellular domain of human GPRC6A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2114003 |
Product Specific Information
PA1-32735 detects GPCR GPRC6A from human samples.
Target Information
GPRC6A is an Orphan-U GPCR with an unknown ligand. G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules, with more than a thousand members predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices and exist in both active and inactive forms. Various activating ligands induce conformational changes in GPCRs, leading to signaling via G-proteins and downstream effectors. Studies have also revealed mechanisms of negative regulation of GPCRs, which are critical for cellular physiology and pharmacological research. GPCR-targeted drugs such as Zyprexa (Eli Lilly) and Claritin (Schering-Plough) exemplify their therapeutic importance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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