Thermo Fisher Scientific Phospho-USP22 (Thr147) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human USP22(Accession Q9UPT9), corresponding to amino acid residues around phosphorylated Thr147. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:USP22,uniProtId:Q9UPT9-1,ncbiNodeId:9606,antigenRange:147,antigenLength:525,antigenImageFileName:PA5-105351_USP22_Q9UPT9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-105351_USP22_Q9UPT9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2816779

Product Specific Information

Antibody detects endogenous levels of USP22 only when phosphorylated at Thr147.

Target Information

Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.