Thermo Fisher Scientific Phospho-USP22 (Thr147) Polyclonal Antibody
USP22 단백질의 Thr147 인산화 부위를 인식하는 rabbit polyclonal antibody. Western blot 및 IHC(P) 검증 완료. 인간, 마우스, 랫트 반응성. 1 mg/mL 액상 형태로 PBS/glycerol buffer에 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human USP22 (Accession Q9UPT9), corresponding to amino acid residues around phosphorylated Thr147. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816779 |
Product Specific Information
This antibody detects endogenous levels of USP22 only when phosphorylated at Thr147.
Target Information
Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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