Thermo Fisher Scientific HIF3A Polyclonal Antibody, MaxPab
HIF3A 단백질을 인식하는 Thermo Fisher Scientific의 다클론 항체로, 인간 시료에 반응하며 Western blot에 적합합니다. PBS 버퍼에 보존되며, -20°C에서 보관합니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific HIF3A Polyclonal Antibody, MaxPab
Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | HIF3A (AAH26308, 1 a.a. ~ 363 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MALGLQRARS TTELRKEKSR DAARSRRSQE TEVLYQLAHT LPFARGVSAH LDKASIMRLT ISYLRMHRLC AAGEWNQVGA GGEPLDACYL KALEGFVMVL TAEGDMAYLS ENVSKHLGLS QLELIGHSIF DFIHPCDQEE LQDALTPQQT LSRRKVEART ERCFSLRMKS TLTSRGRTLN LKAATWKVLN CSGHMRAYKP PAQTSPAGSP DSEPPLQCLV LICEAIPHPG SLEPPLGRGA FLSRHSLDMK FTYCDDRIAE VAGYSPDDLI GCSAYEYIHA LDSDAVSKSI HTCMYPISPG AKPAATWPPA DTRTPQLPIP QDALPPHLNT SSLLPKPQGT VSFLAPSYPV PRSFSPHLPP WWP
Target Information
Cell growth and viability are compromised by oxygen deprivation (hypoxia). Hypoxia-inducible factors (HIFs), including HIF-1 alpha, HIF-1 beta (Arnt 1), EPAS-1 (HIF-2 alpha) and HIF-3 alpha, induce glycolysis, erythropoiesis, and angiogenesis to restore oxygen homeostasis.
HIFs belong to the Per-Arnt-Sim (PAS) domain transcription factor family. In response to hypoxia, HIF-1 alpha forms a heterodimer with Arnt 1 to create the HIF-1 complex, which binds to hypoxia-responsive elements (HRE) in target genes to activate transcription.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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