Thermo Fisher Scientific GPX1 Recombinant Rabbit Monoclonal Antibody (1H10F7)
GPX1 단백질을 인식하는 토끼 단클론 항체로 Western blot, IHC, ELISA에 적합. 인간, 마우스, 랫트 반응성. HEK293 발현 시스템에서 생산된 재조합 항체로 높은 특이성과 재현성 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:12,000–1:72,000 |
| Immunohistochemistry (IHC) | 1:50–200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1H10F7 |
| Immunogen | Recombinant protein of human GPX1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3094341 |
Target Information
Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins that catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. Several isoforms differ in primary structure and localization. The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme and the first of the GPx family to be discovered. GPx2, or gastrointestinal GPx (GI-GPx), is expressed only in the gastrointestinal epithelium. Extracellular plasma GPx (GPx3) is mainly expressed by the kidney and released into the bloodstream. Phospholipid hydroperoxide GPx4 (PH-GPx) is expressed in most tissues and reduces hydroperoxides integrated in membranes and lipids. Most mammalian GPx family members, except for the Cys-containing GPx3 and epididymis-specific GPx5 isoforms, possess selenocysteine at the active site.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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