Thermo Fisher Scientific Prothrombin Monoclonal Antibody (C10)

Applications

Tested Dilution

Publications

Western Blot (WB)

0.5-5 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

5-30 µg/mL

-

Immunocytochemistry (ICC/IF)

5-30 µg/mL

-

Product Specifications

Species Reactivity

Rat

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

C10

Immunogen

Recombinant protein Coagulation Factor II. The antigen corresponds to amino acid range Ser201- Arg323 of the target protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Prothrombin,uniProtId:P18292-1,ncbiNodeId:10114,antigenRange:201-323,antigenLength:617,antigenImageFileName:MA5-41568_Prothrombin_P18292-1_House_mouse.svg,antigenImageFileNamePDP:MA5-41568_Prothrombin_P18292-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2899050

Target Information

Prothrombin or Coagulation factor II, is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.