Thermo Fisher Scientific CTDSP1 Monoclonal Antibody (OTI1A10), TrueMAB
CTDSP1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot, ICC/IF, Flow cytometry에 적합합니다. 고순도 친화 크로마토그래피 정제 제품이며, PBS/BSA/glycerol 버퍼에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A10 |
| Immunogen | Full-length human recombinant CTDSP1 protein produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.61 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CTDSP1 is a class 2C phosphatase with activity dependent on the conserved DxD motif. Expression of CTDSP1 inhibits activated transcription from several promoter-reporter gene constructs, while a mutant lacking phosphatase activity enhances transcription. REST/NRSF complex recruits SCPs to neuronal genes containing RE1 elements, leading to neuronal gene silencing in nonneuronal cells. Phosphatase-inactive SCP forms interfere with REST/NRSF function and promote neuronal differentiation. SCP activity is an evolutionarily conserved transcriptional regulator that silences neuronal genes globally.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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