Thermo Fisher Scientific SCAMP5 Polyclonal Antibody
SCAMP5 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P) 검증 완료. 인간 시료에 반응하며, 항원 친화 크로마토그래피로 정제. 장기 보관 시 -20°C에서 보관 권장.
- 카탈로그번호
- PA561269
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific SCAMP5 Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SCAMP5. Recombinant protein control fragment (Product #RP-95740) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646984 |
Product Specific Information
Immunogen sequence:
GSFSKAQEEW TTGAWKNPHV QQAAQNAAMG AAQGAMNQPQ TQYSATPNYT YSNE
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
Secretory carrier membrane proteins (SCAMPs) are components of post-Golgi membranes and are implicated in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments involved in recycling of cell surface receptors and endocytosis. In neurons, SCAMPs associate with synaptic vesicles, secretion granules, and transporter vesicles.
SCAMPs are composed of four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs, SCAMPs 1–3 contain cytoplasmic N-terminal regions with NPF repeats, which interact with EH domain proteins involved in vesicle budding from plasma membrane or Golgi complex. SCAMPs 4 and 5 lack N-terminal NPF repeats. SCAMPs 1–4 are ubiquitously coexpressed, while SCAMP 5 is detectable only in the brain and expressed late in development, coinciding with the expansion of mature synapses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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