Thermo Fisher Scientific HP1 beta Polyclonal Antibody
HP1 beta 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 인간과 생쥐에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to amino acids 1–159 of Human CBX1 / HP1 beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.54 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1 M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547890 |
Product Specific Information
- Recommended positive controls: HeLa, HepG2, HCT116
- Predicted reactivity: Mouse (100%), Xenopus laevis (92%), Chicken (95%), Chimpanzee (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a highly conserved nonhistone protein, a member of the heterochromatin protein family. It is enriched in heterochromatin and associated with centromeres.
The protein contains:
- An N-terminal chromodomain that binds histone proteins via methylated lysine residues
- A C-terminal chromo shadow domain responsible for homodimerization and interaction with chromatin-associated nonhistone proteins
The protein is involved in epigenetic regulation of chromatin structure and gene expression. Several pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants encoding the same protein have been identified.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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