Thermo Fisher Scientific Mitofilin Polyclonal Antibody
Human Mitofilin 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, ICC/IF, IP에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS/BSA/glycerol buffer에 보존. U87-MG, MCF-7 세포에 양성 대조로 권장. 연구용 전용 제품.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 1–180 of Human Mitofilin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7) with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547893 |
Product Specific Information
- Recommended positive controls: U87-MG, MCF-7
- Predicted reactivity: Mouse (80%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Mitofilin is a transmembrane protein of the inner mitochondrial membrane associated with a large multimeric protein complex (~1200 kDa). It plays a critical role in mitochondrial morphology, fusion, and fission, particularly in forming tubular cristae and cristae junctions. Abnormal mitochondrial morphology has been linked to diseases such as myopathy, cardiomyopathy, rhabdomyosarcoma, and Whartin’s tumor.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
제품 이미지
(해당 이미지 파일: PA5-30419_Mitofilin_Q16891-1_Rabbit.svg, PA5-30419_Mitofilin_Q16891-1_Rabbit_PDP.jpeg)
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