Thermo Fisher Scientific MRPL43 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1.0 µg/mL

Product Specifications

Product Specific Information

This target displays homology in the following species:
Cow: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 79%, Rat: 83%

Target Information

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence and biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. The gene overlaps with SEMA4G at map location 10q24.31 and is transcribed in the opposite direction. Multiple transcript variants encoding at least four different protein isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.