
Thermo Fisher Scientific PDE2A Monoclonal Antibody (OTI3A4), TrueMAB
Human PDE2A 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, ICC/IF, Flow cytometry에 사용 가능. 고순도 친화 크로마토그래피 정제, 액상 형태, -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A4 |
| Immunogen | Full length human recombinant protein of PDE2A produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.94 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
PDE2A (phosphodiesterase 2A) is a 100 kD cyclic nucleotide phosphodiesterase (PDE) with three isoforms (PDE2A1, PDE2A2, PDE2A3) arising from a single gene through alternative splicing. It degrades both cAMP and cGMP, showing higher efficacy for cGMP. PDE2A is expressed in various tissues, predominantly in the brain, localized in the cerebellum and neocortex. It has been implicated in erectile dysfunction and in regulating fluid and inflammatory cell transport across the endothelial barrier.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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