Thermo Fisher Scientific Calsequestrin Polyclonal Antibody
Calsequestrin 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체로, 인체·마우스·래트 시료에 반응합니다. IHC, ICC/IF, ELISA 등 다양한 응용에 적합하며, 고순도 Protein A 정제 및 안정적 액상 형태로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Calsequestrin, amino acids 75–170 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The sarcoplasmic reticulum (SR) is responsible for maintaining intracellular calcium levels in cardiac and skeletal muscle by storing and releasing calcium. Calsequestrin is a calcium-binding protein that sequesters calcium accumulated in the SR during muscle relaxation and is localized to the junctional and corbular (terminal cisternae) regions of the SR. It helps localize calcium near the junctional face of the terminal cisternae for release into the cytosol via the ryanodine receptor. This protein is highly acidic, with a large capacity and moderate to low affinity for calcium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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