Thermo Fisher Scientific GBE1 Polyclonal Antibody
Human GBE1 단백질에 특이적인 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. Glycogen branching enzyme 연구 및 관련 질환 연구용.
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Thermo Fisher Scientific GBE1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GBE1 (Product #RP-95610) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641890 |
Product Specific Information
Immunogen sequence:
LCPDSITIAE DVSGMPALCS PISQGGGGFD YRLAMAIPDK WIQLLKEFKD EDWNMGDIVY TLTNRRYLEK CIAYAESHDQ ALVGDKSLAF WLMDAEMY
Highest antigen sequence identity to the following orthologs:
- Mouse: 95%
- Rat: 69%
Target Information
GBE1 is a glycogen branching enzyme that catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on the same or a neighboring glycogen chain. Branching of the chains increases glycogen solubility and reduces osmotic pressure within cells. The enzyme is most abundant in liver and muscle. Mutations in this gene are associated with glycogen storage disease IV (Andersen’s disease).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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