Thermo Fisher Scientific TYMP Monoclonal Antibody (OTI1G10), TrueMAB
TYMP 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 IHC(P) 실험에 사용 가능. 인간 시료에 반응하며, 동결건조 형태로 제공. TrueMAB 형식으로 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 311–482 of human TYMP produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
TYMP, also known as platelet-derived endothelial cell growth factor (PD-ECGF), thymidine phosphorylase (TP), or gliostatin, catalyzes the reversible phosphorolytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate.
It acts as a chemotactic and mitogenic factor for endothelial cells and functions as a non-heparin-binding angiogenic factor present in platelets.
TYMP is also involved in the metabolic activation of fluoropyrimidines, cytotoxic agents used in cancer therapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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