Thermo Fisher Scientific CXCL15/Lungkine Polyclonal Antibody
CXCL15/Lungkine 단백질을 인식하는 토끼 폴리클로날 항체로, 마우스 시료에 반응합니다. Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합하며, Protein A로 정제된 고품질 항체입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent | |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 | |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from mouse CXCL15 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Interleukin 8 (IL-8, CXCL8) is a 72-amino acid pro-inflammatory factor belonging to the CXC subfamily of chemokines, which bind to cell surface receptors IL-8RA and IL-8RB. IL-8 functions as a chemoattractant and potent angiogenic factor. Its expression and secretion are induced by diverse inflammatory stimuli in various cells, including macrophages and endothelial cells. In endothelial cells, IL-8 is stored in Weibel-Palade bodies. IL-8, first isolated from osteosarcoma cells, contains the ELR motif (Glu-Leu-Arg sequence) and signals through CXCR1 and CXCR2 receptors. Previous names include neutrophil activating protein 1 (NAP-1), granulocyte chemotactic protein 1 (GCP-1), monocyte-derived neutrophil-activating peptide (MONAP), and protein 3-10C. IL-8 and related CXC chemokines form a gene cluster on chromosome 4q. It plays roles in tumor angiogenesis and growth, and in the pathogenesis of bronchiolitis.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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