Thermo Fisher Scientific CHRNA3 Polyclonal Antibody
CHRNA3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화된 제품으로 인간, 마우스, 비인간 영장류, 랫트에서 반응. 고순도 친화성 크로마토그래피 정제, 액상 형태, 안정적인 PBS/glycerol 저장용액 포함.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:500–1:2,000 dilution
- Publications: Not specified
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CHRNA3 (Accession P32297), corresponding to amino acid residues K368–N418 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852476 |
Product Specific Information
Antibody detects endogenous levels of total AChR alpha3.
Target Information
CHRNA3 locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit characterized by adjacent cysteine residues. The encoded protein functions as a ligand-gated ion channel involved in neurotransmission.
Polymorphisms in this gene are associated with increased risk of smoking initiation and susceptibility to lung cancer. Alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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